For people with 1.0X that are experience random CTDs, we think we know the cause.

We've now had two cases where we've worked with someone on this and in both cases it turned out they either had a very small page file (low virtual memory) or had turned off a page file entire.

During the autosave, a virtual copy of the game is created which temporarily increases how much memory the game uses.  For most people, that's meaningless.  But for people with little or not virtual memory, the result is a crash. 

Check your virtual memory settings.  You can do that by right-clicking on my computer, go to properties, click on the advanced tab, click on the performance settings, ciick on advanced, click on the change button in virtual memory.  Make sure your virtual memory is set to at least 2 Gigs.  The game won't use all that of course or anywhere near but we have found that those who run into this almost always have either no page file or very low memory.